Download Cardiac Drug Therapy 7th ed (Contemporary Cardiology) by M. Gabriel, Ed. Khan PDF

By M. Gabriel, Ed. Khan

This booklet addresses the pharmacology and healing program of gear used to regard middle illnesses and high blood pressure. Additions and updates to the 6th variation contain six new chapters on present controversies in cardiac drug treatment resembling the beta blocker factor many cardiologists are shortly grappling with. The publication presents functional recommendation on the right way to deal with cardiac illnesses and addresses the alternative of 1 specific cardiac agent vs. one other.

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Sample text

Pitt B. Regression of left ventricular hypertrophy in patients with hypertension: Blockade of the reninangiotensin-aldosterone system. Circulation 1998;98:1987. 24. Kostis JB, Rosen RC. Central nervous system effects of beta-adrenergic blocking drugs: The role of ancillary properties. Circulation 1987;75:204. 25. Engler RL, Conant J, Maisel A, et al. Lipid solubility determines the relative CNS effects of beta-blocking agents. J Am Coll Cardiol 1986;7:25A. 26. Pitt B. The role of beta-adrenergic blocking agents in preventing sudden cardiac death.

The long-acting preparation provides full 24-h coverage. The BHAT study (33) proved the beneficial effects of propranolol in post-MI patients for the prevention of reinfarction, sudden death, and fatal and nonfatal MIs. Cigarette smoking alters blood levels of propranolol and may mask CP effects. In nonsmokers, however, the drug has been proved effective, whereas only timolol has been proved effective in RCTs and in the post-MI patient. The drug is strongly lipid soluble and therefore has a high uptake in the brain; this may be the reason for fatigue, the rare occurrence of depression, and vivid dreams.

Lipid solubility determines the relative CNS effects of beta-blocking agents. J Am Coll Cardiol 1986;7:25A. 26. Pitt B. The role of beta-adrenergic blocking agents in preventing sudden cardiac death. Circulation 85(Suppl I): 1992;I107. 27. Deanfield J, Wright C, Krikler S. Cigarette smoking and the treatment of angina with propranolol, atenolol and nifedipine. N Engl J Med 1984;310:951. 28. Valimaki ML, Harno K. Lipoprotein lipids and apoproteins during beta-blocker administration: Comparison of penbutolol and atenolol.

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